Beta-keto L-gulonate decarboxylase (BKGD)
Homo sapiens — UniProt Q9H0W9
Data last refreshed: (UniProt release unknown)
Key facts
Beta-keto L-gulonate decarboxylase (BKGD) is a protein from Homo sapiens identified by UniProt accession Q9H0W9, 315 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q9H0W9; gene symbol BKGD.
- Organism: Homo sapiens.
- Length: 315 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, protein measurement and smoking status measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Beta-keto L-gulonate decarboxylase |
|---|---|
| UniProt accession | Q9H0W9 |
| Gene | BKGD |
| Organism | Homo sapiens |
| Length | 315 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.31
- protein measurement · score 0.11
- smoking status measurement · score 0.09
- neutrophil count · score 0.09
- BMI-adjusted waist circumference · score 0.08
- myeloid white cell count · score 0.05
- Familial short QT syndrome · score 0.05
- snowflake vitreoretinal degeneration · score 0.04
- Brugada syndrome · score 0.04
- atrial conduction disease · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0W9-F1 | alphafold | PREDICTED | 97.55 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0W9.
Amino-acid sequence (315 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BKGD?
The strongest Open Targets associations for BKGD are neurodegenerative disease, protein measurement, smoking status measurement, neutrophil count and BMI-adjusted waist circumference.
How long is the BKGD protein?
The Homo sapiens BKGD protein (UniProt Q9H0W9) is 315 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0W9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0W9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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