RING finger protein 208 (RNF208)
Homo sapiens — UniProt Q9H0X6
Data last refreshed: (UniProt release unknown)
Key facts
RING finger protein 208 (RNF208) is a protein from Homo sapiens identified by UniProt accession Q9H0X6, 261 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9H0X6; gene symbol RNF208.
- Organism: Homo sapiens.
- Length: 261 amino acids.
- Top disease associations (Open Targets): triple-negative breast cancer, reticulocyte count and erythrocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RING finger protein 208 |
|---|---|
| UniProt accession | Q9H0X6 |
| Gene | RNF208 |
| Organism | Homo sapiens |
| Length | 261 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- triple-negative breast cancer · score 0.07
- reticulocyte count · score 0.07
- erythrocyte count · score 0.05
- HbA1c measurement · score 0.04
- mean corpuscular volume · score 0.04
- neoplasm · score 0.04
- Hypereosinophilic syndrome · score 0.04
- glomerular filtration rate · score 0.04
- Omenn syndrome · score 0.03
- Takotsubo cardiomyopathy · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0X6-F1 | alphafold | PREDICTED | 61.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0X6.
Amino-acid sequence (261 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RNF208?
The strongest Open Targets associations for RNF208 are triple-negative breast cancer, reticulocyte count, erythrocyte count, HbA1c measurement and mean corpuscular volume.
How long is the RNF208 protein?
The Homo sapiens RNF208 protein (UniProt Q9H0X6) is 261 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0X6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0X6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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