Oxysterol-binding protein-related protein 5 (OSBPL5)
Homo sapiens — UniProt Q9H0X9
Data last refreshed: (UniProt release unknown)
Key facts
Oxysterol-binding protein-related protein 5 (OSBPL5) is a protein from Homo sapiens identified by UniProt accession Q9H0X9, 879 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.
- UniProt accession: Q9H0X9; gene symbol OSBPL5.
- Organism: Homo sapiens.
- Length: 879 amino acids.
- Top disease associations (Open Targets): lean body mass, fat body mass and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Oxysterol-binding protein-related protein 5 |
|---|---|
| UniProt accession | Q9H0X9 |
| Gene | OSBPL5 |
| Organism | Homo sapiens |
| Length | 879 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (47)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.27
- fat body mass · score 0.19
- breast adenocarcinoma · score 0.18
- whole body water mass · score 0.12
- lymphocyte count · score 0.12
- body weight · score 0.10
- base metabolic rate measurement · score 0.09
- non-small cell lung carcinoma · score 0.07
- renal cell carcinoma · score 0.07
- neoplasm · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0X9-F1 | alphafold | PREDICTED | 70.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0X9.
Amino-acid sequence (879 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OSBPL5?
The strongest Open Targets associations for OSBPL5 are lean body mass, fat body mass, breast adenocarcinoma, whole body water mass and lymphocyte count.
How long is the OSBPL5 protein?
The Homo sapiens OSBPL5 protein (UniProt Q9H0X9) is 879 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0X9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0X9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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