Ubiquitin-like-conjugating enzyme ATG10 (ATG10)
Homo sapiens — UniProt Q9H0Y0
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquitin-like-conjugating enzyme ATG10 (ATG10) is a protein from Homo sapiens identified by UniProt accession Q9H0Y0, 220 residues long. MolForge cross-references it against 0 known binders and 94 disease associations.
- UniProt accession: Q9H0Y0; gene symbol ATG10.
- Organism: Homo sapiens.
- Length: 220 amino acids.
- Top disease associations (Open Targets): breast carcinoma, risk-taking behaviour and PHF-tau measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquitin-like-conjugating enzyme ATG10 |
|---|---|
| UniProt accession | Q9H0Y0 |
| Gene | ATG10 |
| Organism | Homo sapiens |
| Length | 220 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (94)
Diseases linked to this target (Open Targets).
- breast carcinoma · score 0.40
- risk-taking behaviour · score 0.36
- PHF-tau measurement · score 0.29
- mathematical ability · score 0.23
- cognitive function measurement · score 0.21
- common carotid intimal medial thickness · score 0.20
- self reported educational attainment · score 0.12
- diet measurement · score 0.10
- alkaline phosphatase measurement · score 0.09
- Red cell distribution width · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0Y0-F1 | alphafold | PREDICTED | 80.22 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0Y0.
Amino-acid sequence (220 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ATG10?
The strongest Open Targets associations for ATG10 are breast carcinoma, risk-taking behaviour, PHF-tau measurement, mathematical ability and cognitive function measurement.
How long is the ATG10 protein?
The Homo sapiens ATG10 protein (UniProt Q9H0Y0) is 220 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0Y0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0Y0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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