Cystatin-11 (CST11)
Homo sapiens — UniProt Q9H112
Data last refreshed: (UniProt release unknown)
Key facts
Cystatin-11 (CST11) is a protein from Homo sapiens identified by UniProt accession Q9H112, 138 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.
- UniProt accession: Q9H112; gene symbol CST11.
- Organism: Homo sapiens.
- Length: 138 amino acids.
- Top disease associations (Open Targets): DNA methylation, cancer and endometriosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cystatin-11 |
|---|---|
| UniProt accession | Q9H112 |
| Gene | CST11 |
| Organism | Homo sapiens |
| Length | 138 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (6)
Diseases linked to this target (Open Targets).
- DNA methylation · score 0.02
- cancer · score 0.01
- endometriosis · score 0.00
- myeloid sarcoma · score 0.00
- Sjogren syndrome · score 0.00
- male infertility · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H112-F1 | alphafold | PREDICTED | 90.92 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H112.
Amino-acid sequence (138 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CST11?
The strongest Open Targets associations for CST11 are DNA methylation, cancer, endometriosis, myeloid sarcoma and Sjogren syndrome.
How long is the CST11 protein?
The Homo sapiens CST11 protein (UniProt Q9H112) is 138 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H112 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H112 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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