Cystatin-like 1 (CSTL1)
Homo sapiens — UniProt Q9H114
Data last refreshed: (UniProt release unknown)
Key facts
Cystatin-like 1 (CSTL1) is a protein from Homo sapiens identified by UniProt accession Q9H114, 145 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q9H114; gene symbol CSTL1.
- Organism: Homo sapiens.
- Length: 145 amino acids.
- Top disease associations (Open Targets): benign neoplasm of adrenal gland, DNA methylation and non-small cell lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cystatin-like 1 |
|---|---|
| UniProt accession | Q9H114 |
| Gene | CSTL1 |
| Organism | Homo sapiens |
| Length | 145 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- benign neoplasm of adrenal gland · score 0.03
- DNA methylation · score 0.02
- non-small cell lung carcinoma · score 0.01
- neoplasm · score 0.01
- cancer · score 0.01
- Crohn's disease · score 0.01
- chronic obstructive pulmonary disease · score 0.00
- metastasis · score 0.00
- Spinal cord injury · score 0.00
- colon adenocarcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H114-F1 | alphafold | PREDICTED | 85.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H114.
Amino-acid sequence (145 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CSTL1?
The strongest Open Targets associations for CSTL1 are benign neoplasm of adrenal gland, DNA methylation, non-small cell lung carcinoma, neoplasm and cancer.
How long is the CSTL1 protein?
The Homo sapiens CSTL1 protein (UniProt Q9H114) is 145 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H114 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H114 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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