Beta-soluble NSF attachment protein (NAPB)
Homo sapiens — UniProt Q9H115
Data last refreshed: (UniProt release unknown)
Key facts
Beta-soluble NSF attachment protein (NAPB) is a protein from Homo sapiens identified by UniProt accession Q9H115, 298 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.
- UniProt accession: Q9H115; gene symbol NAPB.
- Organism: Homo sapiens.
- Length: 298 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Neurodevelopmental disorder and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Beta-soluble NSF attachment protein |
|---|---|
| UniProt accession | Q9H115 |
| Gene | NAPB |
| Organism | Homo sapiens |
| Length | 298 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (54)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.40
- Neurodevelopmental disorder · score 0.37
- genetic disorder · score 0.19
- developmental and epileptic encephalopathy, 1 · score 0.11
- prostate cancer · score 0.11
- West syndrome · score 0.11
- infantile epileptic-dyskinetic encephalopathy · score 0.11
- developmental and epileptic encephalopathy · score 0.11
- prostate carcinoma · score 0.11
- Familial prostate cancer · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H115-F1 | alphafold | PREDICTED | 89.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H115.
Amino-acid sequence (298 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NAPB?
The strongest Open Targets associations for NAPB are neurodegenerative disease, Neurodevelopmental disorder, genetic disorder, developmental and epileptic encephalopathy, 1 and prostate cancer.
How long is the NAPB protein?
The Homo sapiens NAPB protein (UniProt Q9H115) is 298 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H115 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H115 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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