Deoxynucleotidyltransferase terminal-interacting protein 1 (DNTTIP1)
Homo sapiens — UniProt Q9H147
Data last refreshed: (UniProt release unknown)
Key facts
Deoxynucleotidyltransferase terminal-interacting protein 1 (DNTTIP1) is a protein from Homo sapiens identified by UniProt accession Q9H147, 329 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.
- UniProt accession: Q9H147; gene symbol DNTTIP1.
- Organism: Homo sapiens.
- Length: 329 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, mean platelet volume and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Deoxynucleotidyltransferase terminal-interacting protein 1 |
|---|---|
| UniProt accession | Q9H147 |
| Gene | DNTTIP1 |
| Organism | Homo sapiens |
| Length | 329 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (62)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- mean platelet volume · score 0.18
- platelet count · score 0.12
- non-small cell lung carcinoma · score 0.09
- neoplasm · score 0.09
- body height · score 0.07
- nonpapillary renal cell carcinoma · score 0.07
- hepatocellular carcinoma · score 0.07
- thrombocythemia 2 · score 0.06
- essential thrombocythemia · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H147-F1 | alphafold | PREDICTED | 68.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H147.
Amino-acid sequence (329 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DNTTIP1?
The strongest Open Targets associations for DNTTIP1 are neurodegenerative disease, mean platelet volume, platelet count, non-small cell lung carcinoma and neoplasm.
How long is the DNTTIP1 protein?
The Homo sapiens DNTTIP1 protein (UniProt Q9H147) is 329 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H147 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H147 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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