SLIT and NTRK-like protein 2 (SLITRK2)
Homo sapiens — UniProt Q9H156
Data last refreshed: (UniProt release unknown)
Key facts
SLIT and NTRK-like protein 2 (SLITRK2) is a protein from Homo sapiens identified by UniProt accession Q9H156, 845 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.
- UniProt accession: Q9H156; gene symbol SLITRK2.
- Organism: Homo sapiens.
- Length: 845 amino acids.
- Top disease associations (Open Targets): Intellectual disability, 46,XY complete gonadal dysgenesis and Testicular regression syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SLIT and NTRK-like protein 2 |
|---|---|
| UniProt accession | Q9H156 |
| Gene | SLITRK2 |
| Organism | Homo sapiens |
| Length | 845 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (53)
Diseases linked to this target (Open Targets).
- Intellectual disability · score 0.39
- 46,XY complete gonadal dysgenesis · score 0.06
- Testicular regression syndrome · score 0.05
- 46,XX testicular disorder of sex development · score 0.05
- 46,XX gonadal dysgenesis · score 0.05
- cervical cancer · score 0.04
- 46,XX ovotesticular disorder of sex development · score 0.04
- hepatocellular adenoma · score 0.04
- Perrault syndrome · score 0.04
- gonadoblastoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H156-F1 | alphafold | PREDICTED | 67.02 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H156.
Amino-acid sequence (845 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLITRK2?
The strongest Open Targets associations for SLITRK2 are Intellectual disability, 46,XY complete gonadal dysgenesis, Testicular regression syndrome, 46,XX testicular disorder of sex development and 46,XX gonadal dysgenesis.
How long is the SLITRK2 protein?
The Homo sapiens SLITRK2 protein (UniProt Q9H156) is 845 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H156 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H156 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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