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Cadherin-19 (CDH19)

Homo sapiens — UniProt Q9H159

Gene: CDH19Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Cadherin-19 (CDH19) is a protein from Homo sapiens identified by UniProt accession Q9H159, 772 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.

  • UniProt accession: Q9H159; gene symbol CDH19.
  • Organism: Homo sapiens.
  • Length: 772 amino acids.
  • Top disease associations (Open Targets): chronotype measurement, diet measurement and self reported educational attainment.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCadherin-19
UniProt accessionQ9H159
GeneCDH19
OrganismHomo sapiens
Length772 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (56)

Diseases linked to this target (Open Targets).

  • chronotype measurement · score 0.37
  • diet measurement · score 0.26
  • self reported educational attainment · score 0.25
  • Ovarian Endometriosis · score 0.20
  • mathematical ability · score 0.19
  • drug use measurement · score 0.12
  • hepatocellular carcinoma · score 0.06
  • DNA methylation · score 0.05
  • breast cancer · score 0.05
  • triple-negative breast cancer · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H159-F1alphafoldPREDICTED78.09—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H159.

Amino-acid sequence (772 residues)

MNCYLLLRFM LGIPLLWPCL GATENSQTKK VKQPVRSHLR VKRGWVWNQF FVPEEMNTTS HHIGQLRSDL DNGNNSFQYK LLGAGAGSTF IIDERTGDIY AIQKLDREER SLYILRAQVI DIATGRAVEP ESEFVIKVSD INDNEPKFLD EPYEAIVPEM SPEGTLVIQV TASDADDPSS GNNARLLYSL LQGQPYFSVE PTTGVIRISS KMDRELQDEY WVIIQAKDMI GQPGALSGTT SVLIKLSDVN DNKPIFKESL YRLTVSESAP TGTSIGTIMA YDNDIGENAE MDYSIEEDDS QTFDIITNHE TQEGIVILKK KVDFEHQNHY GIRAKVKNHH VPEQLMKYHT EASTTFIKIQ VEDVDEPPLF LLPYYVFEVF EETPQGSFVG VVSATDPDNR KSPIRYSITR SKVFNINDNG TITTSNSLDR EISAWYNLSI TATEKYNIEQ ISSIPLYVQV LNINDHAPEF SQYYETYVCE NAGSGQVIQT ISAVDRDESI EEHHFYFNLS VEDTNNSSFT IIDNQDNTAV ILTNRTGFNL QEEPVFYISI LIADNGIPSL TSTNTLTIHV CDCGDSGSTQ TCQYQELVLS MGFKTEVIIA ILICIMIIFG FIFLTLGLKQ RRKQILFPEK SEDFRENIFQ YDDEGGGEED TEAFDIAELR SSTIMRERKT RKTTSAEIRS LYRQSLQVGP DSAIFRKFIL EKLEEANTDP CAPPFDSLQT YAFEGTGSLA GSLSSLESAV SDQDESYDYL NELGPRFKRL ACMFGSAVQS NN

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CDH19?

The strongest Open Targets associations for CDH19 are chronotype measurement, diet measurement, self reported educational attainment, Ovarian Endometriosis and mathematical ability.

How long is the CDH19 protein?

The Homo sapiens CDH19 protein (UniProt Q9H159) is 772 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H159
GeneCDH19
OrganismHomo sapiens
Length772
Binders0
Diseases56
View on UniProt