BCL11 transcription factor A (BCL11A)
Homo sapiens — UniProt Q9H165
Data last refreshed: (UniProt release unknown)
Key facts
BCL11 transcription factor A (BCL11A) is a protein from Homo sapiens identified by UniProt accession Q9H165, 835 residues long. MolForge cross-references it against 0 known binders and 454 disease associations.
- UniProt accession: Q9H165; gene symbol BCL11A.
- Organism: Homo sapiens.
- Length: 835 amino acids.
- Top disease associations (Open Targets): Dias-Logan syndrome, Intellectual disability and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BCL11 transcription factor A |
|---|---|
| UniProt accession | Q9H165 |
| Gene | BCL11A |
| Organism | Homo sapiens |
| Length | 835 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (454)
Diseases linked to this target (Open Targets).
- Dias-Logan syndrome · score 0.74
- Intellectual disability · score 0.64
- cancer · score 0.51
- mean corpuscular volume · score 0.51
- self reported educational attainment · score 0.50
- genetic disorder · score 0.50
- Red cell distribution width · score 0.49
- erythrocyte count · score 0.49
- mean corpuscular hemoglobin · score 0.48
- reticulocyte count · score 0.48
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H165-F1 | alphafold | PREDICTED | 52.32 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H165.
Amino-acid sequence (835 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BCL11A?
The strongest Open Targets associations for BCL11A are Dias-Logan syndrome, Intellectual disability, cancer, mean corpuscular volume and self reported educational attainment.
How long is the BCL11A protein?
The Homo sapiens BCL11A protein (UniProt Q9H165) is 835 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H165 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H165 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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