ATP-binding cassette sub-family G member 4 (ABCG4)
Homo sapiens — UniProt Q9H172
Data last refreshed: (UniProt release unknown)
Key facts
ATP-binding cassette sub-family G member 4 (ABCG4) is a protein from Homo sapiens identified by UniProt accession Q9H172, 646 residues long. MolForge cross-references it against 0 known binders and 59 disease associations.
- UniProt accession: Q9H172; gene symbol ABCG4.
- Organism: Homo sapiens.
- Length: 646 amino acids.
- Top disease associations (Open Targets): neutrophil percentage of leukocytes, monocyte count and calcium measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ATP-binding cassette sub-family G member 4 |
|---|---|
| UniProt accession | Q9H172 |
| Gene | ABCG4 |
| Organism | Homo sapiens |
| Length | 646 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (59)
Diseases linked to this target (Open Targets).
- neutrophil percentage of leukocytes · score 0.18
- monocyte count · score 0.17
- calcium measurement · score 0.16
- HbA1c measurement · score 0.15
- sex hormone-binding globulin measurement · score 0.15
- cutaneous melanoma · score 0.13
- prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- Familial prostate cancer · score 0.11
- reticulocyte count · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H172-F1 | alphafold | PREDICTED | 83.21 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H172.
Amino-acid sequence (646 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ABCG4?
The strongest Open Targets associations for ABCG4 are neutrophil percentage of leukocytes, monocyte count, calcium measurement, HbA1c measurement and sex hormone-binding globulin measurement.
How long is the ABCG4 protein?
The Homo sapiens ABCG4 protein (UniProt Q9H172) is 646 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H172 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H172 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.