Syntenin-2 (SDCBP2)
Homo sapiens — UniProt Q9H190
Data last refreshed: (UniProt release unknown)
Key facts
Syntenin-2 (SDCBP2) is a protein from Homo sapiens identified by UniProt accession Q9H190, 292 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q9H190; gene symbol SDCBP2.
- Organism: Homo sapiens.
- Length: 292 amino acids.
- Top disease associations (Open Targets): blood protein measurement, mean platelet volume and glomerular filtration rate.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Syntenin-2 |
|---|---|
| UniProt accession | Q9H190 |
| Gene | SDCBP2 |
| Organism | Homo sapiens |
| Length | 292 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.16
- mean platelet volume · score 0.15
- glomerular filtration rate · score 0.11
- gonorrhea · score 0.07
- neoplasm · score 0.03
- esophageal squamous cell carcinoma · score 0.03
- colorectal cancer · score 0.02
- colorectal adenocarcinoma · score 0.02
- acute myeloid leukemia · score 0.02
- Crohn's disease · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H190-F1 | alphafold | PREDICTED | 81.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H190.
Amino-acid sequence (292 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SDCBP2?
The strongest Open Targets associations for SDCBP2 are blood protein measurement, mean platelet volume, glomerular filtration rate, gonorrhea and neoplasm.
How long is the SDCBP2 protein?
The Homo sapiens SDCBP2 protein (UniProt Q9H190) is 292 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H190 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H190 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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