Lysophosphatidic acid receptor 5 (LPAR5)
Homo sapiens — UniProt Q9H1C0
Data last refreshed: (UniProt release unknown)
Key facts
Lysophosphatidic acid receptor 5 (LPAR5) is a protein from Homo sapiens identified by UniProt accession Q9H1C0, 372 residues long. MolForge cross-references it against 0 known binders and 101 disease associations.
- UniProt accession: Q9H1C0; gene symbol LPAR5.
- Organism: Homo sapiens.
- Length: 372 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, mean corpuscular hemoglobin and glioblastoma multiforme.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Lysophosphatidic acid receptor 5 |
|---|---|
| UniProt accession | Q9H1C0 |
| Gene | LPAR5 |
| Organism | Homo sapiens |
| Length | 372 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (101)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.32
- mean corpuscular hemoglobin · score 0.29
- glioblastoma multiforme · score 0.26
- ovarian cancer · score 0.24
- triglyceride measurement · score 0.24
- mean corpuscular hemoglobin concentration · score 0.21
- vital capacity · score 0.20
- sex hormone-binding globulin measurement · score 0.15
- mean reticulocyte volume · score 0.13
- low grade glioma · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H1C0-F1 | alphafold | PREDICTED | 84.01 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H1C0.
Amino-acid sequence (372 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LPAR5?
The strongest Open Targets associations for LPAR5 are mean corpuscular volume, mean corpuscular hemoglobin, glioblastoma multiforme, ovarian cancer and triglyceride measurement.
How long is the LPAR5 protein?
The Homo sapiens LPAR5 protein (UniProt Q9H1C0) is 372 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H1C0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H1C0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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