Glycosyltransferase 8 domain-containing protein 2 (GLT8D2)
Homo sapiens — UniProt Q9H1C3
Data last refreshed: (UniProt release unknown)
Key facts
Glycosyltransferase 8 domain-containing protein 2 (GLT8D2) is a protein from Homo sapiens identified by UniProt accession Q9H1C3, 349 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.
- UniProt accession: Q9H1C3; gene symbol GLT8D2.
- Organism: Homo sapiens.
- Length: 349 amino acids.
- Top disease associations (Open Targets): body height, central corneal thickness and appendicular lean mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glycosyltransferase 8 domain-containing protein 2 |
|---|---|
| UniProt accession | Q9H1C3 |
| Gene | GLT8D2 |
| Organism | Homo sapiens |
| Length | 349 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (63)
Diseases linked to this target (Open Targets).
- body height · score 0.43
- central corneal thickness · score 0.41
- appendicular lean mass · score 0.33
- corneal topography · score 0.26
- intraocular pressure measurement · score 0.24
- BMI-adjusted waist circumference · score 0.23
- cor pulmonale · score 0.11
- Phlebitis · score 0.08
- Thrombophlebitis · score 0.08
- pulmonary embolism · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H1C3-F1 | alphafold | PREDICTED | 87.90 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H1C3.
Amino-acid sequence (349 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GLT8D2?
The strongest Open Targets associations for GLT8D2 are body height, central corneal thickness, appendicular lean mass, corneal topography and intraocular pressure measurement.
How long is the GLT8D2 protein?
The Homo sapiens GLT8D2 protein (UniProt Q9H1C3) is 349 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H1C3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H1C3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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