Protein unc-93 homolog B1 (UNC93B1)
Homo sapiens — UniProt Q9H1C4
Data last refreshed: (UniProt release unknown)
Key facts
Protein unc-93 homolog B1 (UNC93B1) is a protein from Homo sapiens identified by UniProt accession Q9H1C4, 597 residues long. MolForge cross-references it against 0 known binders and 209 disease associations.
- UniProt accession: Q9H1C4; gene symbol UNC93B1.
- Organism: Homo sapiens.
- Length: 597 amino acids.
- Top disease associations (Open Targets): Herpetic encephalitis, inborn error of immunity and herpes simplex encephalitis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein unc-93 homolog B1 |
|---|---|
| UniProt accession | Q9H1C4 |
| Gene | UNC93B1 |
| Organism | Homo sapiens |
| Length | 597 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (209)
Diseases linked to this target (Open Targets).
- Herpetic encephalitis · score 0.71
- inborn error of immunity · score 0.38
- herpes simplex encephalitis · score 0.37
- drug use measurement · score 0.10
- acute myeloid leukemia · score 0.07
- Familial hemophagocytic lymphohistiocytosis · score 0.06
- common variable immunodeficiency · score 0.05
- immunodeficiency 89 and autoimmunity · score 0.05
- X-linked lymphoproliferative disease · score 0.05
- isolated agammaglobulinemia · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H1C4-F1 | alphafold | PREDICTED | 79.55 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H1C4.
Amino-acid sequence (597 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UNC93B1?
The strongest Open Targets associations for UNC93B1 are Herpetic encephalitis, inborn error of immunity, herpes simplex encephalitis, drug use measurement and acute myeloid leukemia.
How long is the UNC93B1 protein?
The Homo sapiens UNC93B1 protein (UniProt Q9H1C4) is 597 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H1C4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H1C4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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