Cysteine-rich transmembrane module-containing protein 1 (CYSTM1)
Homo sapiens — UniProt Q9H1C7
Data last refreshed: (UniProt release unknown)
Key facts
Cysteine-rich transmembrane module-containing protein 1 (CYSTM1) is a protein from Homo sapiens identified by UniProt accession Q9H1C7, 97 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.
- UniProt accession: Q9H1C7; gene symbol CYSTM1.
- Organism: Homo sapiens.
- Length: 97 amino acids.
- Top disease associations (Open Targets): bilirubin measurement, low density lipoprotein cholesterol measurement and cognitive function measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cysteine-rich transmembrane module-containing protein 1 |
|---|---|
| UniProt accession | Q9H1C7 |
| Gene | CYSTM1 |
| Organism | Homo sapiens |
| Length | 97 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (46)
Diseases linked to this target (Open Targets).
- bilirubin measurement · score 0.29
- low density lipoprotein cholesterol measurement · score 0.27
- cognitive function measurement · score 0.26
- balding measurement · score 0.24
- serum gamma-glutamyl transferase measurement · score 0.23
- intelligence · score 0.21
- total cholesterol measurement · score 0.20
- mathematical ability · score 0.20
- self reported educational attainment · score 0.18
- blood phosphate measurement · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H1C7-F1 | alphafold | PREDICTED | 62.83 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H1C7.
Amino-acid sequence (97 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CYSTM1?
The strongest Open Targets associations for CYSTM1 are bilirubin measurement, low density lipoprotein cholesterol measurement, cognitive function measurement, balding measurement and serum gamma-glutamyl transferase measurement.
How long is the CYSTM1 protein?
The Homo sapiens CYSTM1 protein (UniProt Q9H1C7) is 97 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H1C7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H1C7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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