Ribonuclease 7 (RNASE7)
Homo sapiens — UniProt Q9H1E1
Data last refreshed: (UniProt release unknown)
Key facts
Ribonuclease 7 (RNASE7) is a protein from Homo sapiens identified by UniProt accession Q9H1E1, 156 residues long. MolForge cross-references it against 0 known binders and 71 disease associations.
- UniProt accession: Q9H1E1; gene symbol RNASE7.
- Organism: Homo sapiens.
- Length: 156 amino acids.
- Top disease associations (Open Targets): ovarian cancer, endometrial cancer and infection.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ribonuclease 7 |
|---|---|
| UniProt accession | Q9H1E1 |
| Gene | RNASE7 |
| Organism | Homo sapiens |
| Length | 156 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (71)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.18
- endometrial cancer · score 0.15
- infection · score 0.06
- infect · score 0.06
- esophageal adenocarcinoma · score 0.04
- psoriasis · score 0.04
- bacterial urinary tract infection · score 0.03
- pyelonephritis · score 0.03
- oral squamous cell carcinoma · score 0.02
- acute pyelonephritis · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H1E1-F1 | alphafold | PREDICTED | 90.51 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H1E1.
Amino-acid sequence (156 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RNASE7?
The strongest Open Targets associations for RNASE7 are ovarian cancer, endometrial cancer, infection, infect and esophageal adenocarcinoma.
How long is the RNASE7 protein?
The Homo sapiens RNASE7 protein (UniProt Q9H1E1) is 156 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H1E1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H1E1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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