Gametocyte-specific factor 1-like (GTSF1L)
Homo sapiens — UniProt Q9H1H1
Data last refreshed: (UniProt release unknown)
Key facts
Gametocyte-specific factor 1-like (GTSF1L) is a protein from Homo sapiens identified by UniProt accession Q9H1H1, 148 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q9H1H1; gene symbol GTSF1L.
- Organism: Homo sapiens.
- Length: 148 amino acids.
- Top disease associations (Open Targets): PHF-tau measurement, mean corpuscular volume and mean reticulocyte volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Gametocyte-specific factor 1-like |
|---|---|
| UniProt accession | Q9H1H1 |
| Gene | GTSF1L |
| Organism | Homo sapiens |
| Length | 148 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- PHF-tau measurement · score 0.11
- mean corpuscular volume · score 0.09
- mean reticulocyte volume · score 0.09
- mean corpuscular hemoglobin · score 0.07
- Abnormality of refraction · score 0.06
- body fat percentage · score 0.05
- leukocyte count · score 0.05
- transient myeloproliferative syndrome · score 0.04
- gluthathione peroxidase deficiency · score 0.04
- metabolite measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H1H1-F1 | alphafold | PREDICTED | 74.93 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H1H1.
Amino-acid sequence (148 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GTSF1L?
The strongest Open Targets associations for GTSF1L are PHF-tau measurement, mean corpuscular volume, mean reticulocyte volume, mean corpuscular hemoglobin and Abnormality of refraction.
How long is the GTSF1L protein?
The Homo sapiens GTSF1L protein (UniProt Q9H1H1) is 148 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H1H1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H1H1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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