Protein Wnt-5b (WNT5B)
Homo sapiens — UniProt Q9H1J7
Data last refreshed: (UniProt release unknown)
Key facts
Protein Wnt-5b (WNT5B) is a protein from Homo sapiens identified by UniProt accession Q9H1J7, 359 residues long. MolForge cross-references it against 0 known binders and 139 disease associations.
- UniProt accession: Q9H1J7; gene symbol WNT5B.
- Organism: Homo sapiens.
- Length: 359 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, bone quantitative ultrasound measurement and bone density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein Wnt-5b |
|---|---|
| UniProt accession | Q9H1J7 |
| Gene | WNT5B |
| Organism | Homo sapiens |
| Length | 359 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (139)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.44
- bone quantitative ultrasound measurement · score 0.42
- bone density · score 0.40
- electrocardiography · score 0.30
- protein measurement · score 0.28
- brain volume measurement · score 0.27
- Vertigo · score 0.24
- endometrial cancer · score 0.18
- sitting height measurement · score 0.12
- vital capacity · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H1J7-F1 | alphafold | PREDICTED | 89.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H1J7.
Amino-acid sequence (359 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WNT5B?
The strongest Open Targets associations for WNT5B are heel bone mineral density, bone quantitative ultrasound measurement, bone density, electrocardiography and protein measurement.
How long is the WNT5B protein?
The Homo sapiens WNT5B protein (UniProt Q9H1J7) is 359 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H1J7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H1J7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.