Talin rod domain-containing protein 1 (TLNRD1)
Homo sapiens — UniProt Q9H1K6
Data last refreshed: (UniProt release unknown)
Key facts
Talin rod domain-containing protein 1 (TLNRD1) is a protein from Homo sapiens identified by UniProt accession Q9H1K6, 362 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q9H1K6; gene symbol TLNRD1.
- Organism: Homo sapiens.
- Length: 362 amino acids.
- Top disease associations (Open Targets): neutrophil percentage of leukocytes, gut microbiome measurement and IGF-1 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Talin rod domain-containing protein 1 |
|---|---|
| UniProt accession | Q9H1K6 |
| Gene | TLNRD1 |
| Organism | Homo sapiens |
| Length | 362 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- neutrophil percentage of leukocytes · score 0.13
- gut microbiome measurement · score 0.13
- IGF-1 measurement · score 0.07
- breast cancer · score 0.04
- coronary artery disease · score 0.03
- high density lipoprotein cholesterol measurement · score 0.03
- urate measurement · score 0.02
- creatinine measurement · score 0.02
- cerebral cavernous malformation · score 0.02
- hepatocellular carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H1K6-F1 | alphafold | PREDICTED | 87.37 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H1K6.
Amino-acid sequence (362 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TLNRD1?
The strongest Open Targets associations for TLNRD1 are neutrophil percentage of leukocytes, gut microbiome measurement, IGF-1 measurement, breast cancer and coronary artery disease.
How long is the TLNRD1 protein?
The Homo sapiens TLNRD1 protein (UniProt Q9H1K6) is 362 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H1K6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H1K6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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