Nucleoporin-62 C-terminal-like protein (NUP62CL)
Homo sapiens — UniProt Q9H1M0
Data last refreshed: (UniProt release unknown)
Key facts
Nucleoporin-62 C-terminal-like protein (NUP62CL) is a protein from Homo sapiens identified by UniProt accession Q9H1M0, 184 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q9H1M0; gene symbol NUP62CL.
- Organism: Homo sapiens.
- Length: 184 amino acids.
- Top disease associations (Open Targets): oral squamous cell carcinoma, lung adenocarcinoma and hemolytic anemia due to glutathione reductase deficiency.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nucleoporin-62 C-terminal-like protein |
|---|---|
| UniProt accession | Q9H1M0 |
| Gene | NUP62CL |
| Organism | Homo sapiens |
| Length | 184 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- oral squamous cell carcinoma · score 0.08
- lung adenocarcinoma · score 0.06
- hemolytic anemia due to glutathione reductase deficiency · score 0.04
- neoplasm · score 0.04
- granular corneal dystrophy type I · score 0.04
- X-linked endothelial corneal dystrophy · score 0.04
- lattice corneal dystrophy type I · score 0.04
- Fuchs endothelial corneal dystrophy · score 0.03
- granular corneal dystrophy type II · score 0.03
- Familial ocular anterior segment mesenchymal dysgenesis · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H1M0-F1 | alphafold | PREDICTED | 73.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H1M0.
Amino-acid sequence (184 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NUP62CL?
The strongest Open Targets associations for NUP62CL are oral squamous cell carcinoma, lung adenocarcinoma, hemolytic anemia due to glutathione reductase deficiency, neoplasm and granular corneal dystrophy type I.
How long is the NUP62CL protein?
The Homo sapiens NUP62CL protein (UniProt Q9H1M0) is 184 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H1M0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H1M0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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