Adenosine 3'-phospho 5'-phosphosulfate transporter 2 (SLC35B3)
Homo sapiens — UniProt Q9H1N7
Data last refreshed: (UniProt release unknown)
Key facts
Adenosine 3'-phospho 5'-phosphosulfate transporter 2 (SLC35B3) is a protein from Homo sapiens identified by UniProt accession Q9H1N7, 401 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9H1N7; gene symbol SLC35B3.
- Organism: Homo sapiens.
- Length: 401 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): motion sickness, alcohol drinking and autosomal dominant compelling helio-ophthalmic outburst syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Adenosine 3'-phospho 5'-phosphosulfate transporter 2 |
|---|---|
| UniProt accession | Q9H1N7 |
| Gene | SLC35B3 |
| Organism | Homo sapiens |
| Length | 401 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- motion sickness · score 0.20
- alcohol drinking · score 0.14
- autosomal dominant compelling helio-ophthalmic outburst syndrome · score 0.13
- brain volume measurement · score 0.13
- cutaneous melanoma · score 0.12
- adolescent idiopathic scoliosis · score 0.08
- colitis · score 0.01
- Abnormal sperm morphology · score 0.01
- juvenile dermatomyositis · score 0.01
- ovarian carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H1N7-F1 | alphafold | PREDICTED | 77.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H1N7.
Amino-acid sequence (401 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC35B3?
The strongest Open Targets associations for SLC35B3 are motion sickness, alcohol drinking, autosomal dominant compelling helio-ophthalmic outburst syndrome, brain volume measurement and cutaneous melanoma.
How long is the SLC35B3 protein?
The Homo sapiens SLC35B3 protein (UniProt Q9H1N7) is 401 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H1N7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H1N7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.