PC-esterase domain-containing protein 1A (PCED1A)
Homo sapiens — UniProt Q9H1Q7
Data last refreshed: (UniProt release unknown)
Key facts
PC-esterase domain-containing protein 1A (PCED1A) is a protein from Homo sapiens identified by UniProt accession Q9H1Q7, 454 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q9H1Q7; gene symbol PCED1A.
- Organism: Homo sapiens.
- Length: 454 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, monocyte count and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | PC-esterase domain-containing protein 1A |
|---|---|
| UniProt accession | Q9H1Q7 |
| Gene | PCED1A |
| Organism | Homo sapiens |
| Length | 454 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.20
- monocyte count · score 0.16
- genetic disorder · score 0.12
- myeloid white cell count · score 0.11
- neutrophil count · score 0.11
- leukocyte count · score 0.07
- lymphocyte percentage of leukocytes · score 0.06
- Immature Reticulocyte Fraction Measurement · score 0.06
- body mass index · score 0.05
- reticulocyte count · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H1Q7-F1 | alphafold | PREDICTED | 70.32 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H1Q7.
Amino-acid sequence (454 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCED1A?
The strongest Open Targets associations for PCED1A are neurodegenerative disease, monocyte count, genetic disorder, myeloid white cell count and neutrophil count.
How long is the PCED1A protein?
The Homo sapiens PCED1A protein (UniProt Q9H1Q7) is 454 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H1Q7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H1Q7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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