Dual specificity protein phosphatase 15 (DUSP15)
Homo sapiens — UniProt Q9H1R2
Data last refreshed: (UniProt release unknown)
Key facts
Dual specificity protein phosphatase 15 (DUSP15) is a protein from Homo sapiens identified by UniProt accession Q9H1R2, 295 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.
- UniProt accession: Q9H1R2; gene symbol DUSP15.
- Organism: Homo sapiens.
- Length: 295 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, alkaline phosphatase measurement and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dual specificity protein phosphatase 15 |
|---|---|
| UniProt accession | Q9H1R2 |
| Gene | DUSP15 |
| Organism | Homo sapiens |
| Length | 295 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.29
- alkaline phosphatase measurement · score 0.14
- mean corpuscular volume · score 0.07
- Red cell distribution width · score 0.06
- mean corpuscular hemoglobin · score 0.06
- mean corpuscular hemoglobin concentration · score 0.06
- attention deficit hyperactivity disorder · score 0.06
- Tourette syndrome · score 0.05
- schizophrenia 15 · score 0.05
- attention deficit-hyperactivity disorder 8 · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H1R2-F1 | alphafold | PREDICTED | 66.40 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H1R2.
Amino-acid sequence (295 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DUSP15?
The strongest Open Targets associations for DUSP15 are neurodegenerative disease, alkaline phosphatase measurement, mean corpuscular volume, Red cell distribution width and mean corpuscular hemoglobin.
How long is the DUSP15 protein?
The Homo sapiens DUSP15 protein (UniProt Q9H1R2) is 295 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H1R2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H1R2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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