Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51 (SLC25A51)
Homo sapiens — UniProt Q9H1U9
Data last refreshed: (UniProt release unknown)
Key facts
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51 (SLC25A51) is a protein from Homo sapiens identified by UniProt accession Q9H1U9, 297 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q9H1U9; gene symbol SLC25A51.
- Organism: Homo sapiens.
- Length: 297 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): neurodegenerative disease, hemorrhagic disease and systolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51 |
|---|---|
| UniProt accession | Q9H1U9 |
| Gene | SLC25A51 |
| Organism | Homo sapiens |
| Length | 297 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- hemorrhagic disease · score 0.18
- systolic blood pressure · score 0.17
- pulse pressure measurement · score 0.09
- reticulocyte count · score 0.08
- reticulocyte measurement · score 0.08
- balding measurement · score 0.07
- FEV/FVC ratio · score 0.06
- hair shape measurement · score 0.06
- acne · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H1U9-F1 | alphafold | PREDICTED | 82.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H1U9.
Amino-acid sequence (297 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC25A51?
The strongest Open Targets associations for SLC25A51 are neurodegenerative disease, hemorrhagic disease, systolic blood pressure, pulse pressure measurement and reticulocyte count.
How long is the SLC25A51 protein?
The Homo sapiens SLC25A51 protein (UniProt Q9H1U9) is 297 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H1U9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H1U9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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