Sodium-dependent neutral amino acid transporter SLC6A17 (SLC6A17)
Homo sapiens — UniProt Q9H1V8
Data last refreshed: (UniProt release unknown)
Key facts
Sodium-dependent neutral amino acid transporter SLC6A17 (SLC6A17) is a protein from Homo sapiens identified by UniProt accession Q9H1V8, 727 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q9H1V8; gene symbol SLC6A17.
- Organism: Homo sapiens.
- Length: 727 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): progressive essential tremor-speech impairment-facial dysmorphism-intellectual disability-abnormal behavior syndrome, skin pigmentation and sunburn.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sodium-dependent neutral amino acid transporter SLC6A17 |
|---|---|
| UniProt accession | Q9H1V8 |
| Gene | SLC6A17 |
| Organism | Homo sapiens |
| Length | 727 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- progressive essential tremor-speech impairment-facial dysmorphism-intellectual disability-abnormal behavior syndrome · score 0.67
- skin pigmentation · score 0.30
- sunburn · score 0.27
- keratinocyte carcinoma · score 0.27
- neutrophil count · score 0.22
- leukocyte count · score 0.18
- myeloid white cell count · score 0.18
- central nervous system cancer · score 0.04
- lung carcinoma · score 0.04
- small cell lung carcinoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H1V8-F1 | alphafold | PREDICTED | 81.00 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H1V8.
Amino-acid sequence (727 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC6A17?
The strongest Open Targets associations for SLC6A17 are progressive essential tremor-speech impairment-facial dysmorphism-intellectual disability-abnormal behavior syndrome, skin pigmentation, sunburn, keratinocyte carcinoma and neutrophil count.
How long is the SLC6A17 protein?
The Homo sapiens SLC6A17 protein (UniProt Q9H1V8) is 727 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H1V8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H1V8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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