DnaJ homolog subfamily C member 25 (DNAJC25)
Homo sapiens — UniProt Q9H1X3
Data last refreshed: (UniProt release unknown)
Key facts
DnaJ homolog subfamily C member 25 (DNAJC25) is a protein from Homo sapiens identified by UniProt accession Q9H1X3, 360 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q9H1X3; gene symbol DNAJC25.
- Organism: Homo sapiens.
- Length: 360 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, monocyte count and lymphocyte:monocyte ratio.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | DnaJ homolog subfamily C member 25 |
|---|---|
| UniProt accession | Q9H1X3 |
| Gene | DNAJC25 |
| Organism | Homo sapiens |
| Length | 360 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.34
- monocyte count · score 0.05
- lymphocyte:monocyte ratio · score 0.05
- neutrophil count · score 0.03
- lymphocyte count · score 0.03
- Red cell distribution width · score 0.02
- BMI-adjusted waist-hip ratio · score 0.02
- eosinophil count · score 0.02
- red blood cell density measurement · score 0.02
- brain aneurysm · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H1X3-F1 | alphafold | PREDICTED | 82.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H1X3.
Amino-acid sequence (360 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DNAJC25?
The strongest Open Targets associations for DNAJC25 are neurodegenerative disease, monocyte count, lymphocyte:monocyte ratio, neutrophil count and lymphocyte count.
How long is the DNAJC25 protein?
The Homo sapiens DNAJC25 protein (UniProt Q9H1X3) is 360 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H1X3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H1X3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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