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Opsin-3 (OPN3)

Homo sapiens — UniProt Q9H1Y3

Gene: OPN3Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Opsin-3 (OPN3) is a protein from Homo sapiens identified by UniProt accession Q9H1Y3, 402 residues long. MolForge cross-references it against 0 known binders and 106 disease associations.

  • UniProt accession: Q9H1Y3; gene symbol OPN3.
  • Organism: Homo sapiens.
  • Length: 402 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, drug use measurement and self reported educational attainment.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameOpsin-3
UniProt accessionQ9H1Y3
GeneOPN3
OrganismHomo sapiens
Length402 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (106)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.26
  • drug use measurement · score 0.20
  • self reported educational attainment · score 0.13
  • mathematical ability · score 0.13
  • urate measurement · score 0.11
  • bone density · score 0.11
  • Myopia · score 0.08
  • myopia · score 0.08
  • cancer · score 0.08
  • lung adenocarcinoma · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H1Y3-F1alphafoldPREDICTED79.78—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H1Y3.

Amino-acid sequence (402 residues)

MYSGNRSGGH GYWDGGGAAG AEGPAPAGTL SPAPLFSPGT YERLALLLGS IGLLGVGNNL LVLVLYYKFQ RLRTPTHLLL VNISLSDLLV SLFGVTFTFV SCLRNGWVWD TVGCVWDGFS GSLFGIVSIA TLTVLAYERY IRVVHARVIN FSWAWRAITY IWLYSLAWAG APLLGWNRYI LDVHGLGCTV DWKSKDANDS SFVLFLFLGC LVVPLGVIAH CYGHILYSIR MLRCVEDLQT IQVIKILKYE KKLAKMCFLM IFTFLVCWMP YIVICFLVVN GHGHLVTPTI SIVSYLFAKS NTVYNPVIYV FMIRKFRRSL LQLLCLRLLR CQRPAKDLPA AGSEMQIRPI VMSQKDGDRP KKKVTFNSSS IIFIITSDES LSVDDSDKTN GSKVDVIQVR PL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with OPN3?

The strongest Open Targets associations for OPN3 are neurodegenerative disease, drug use measurement, self reported educational attainment, mathematical ability and urate measurement.

How long is the OPN3 protein?

The Homo sapiens OPN3 protein (UniProt Q9H1Y3) is 402 amino acids long.

Browse: Targets: O · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H1Y3
GeneOPN3
OrganismHomo sapiens
Length402
Binders0
Diseases106
View on UniProt