WD repeat-containing protein 13 (WDR13)
Homo sapiens — UniProt Q9H1Z4
Data last refreshed: (UniProt release unknown)
Key facts
WD repeat-containing protein 13 (WDR13) is a protein from Homo sapiens identified by UniProt accession Q9H1Z4, 485 residues long. MolForge cross-references it against 0 known binders and 60 disease associations.
- UniProt accession: Q9H1Z4; gene symbol WDR13.
- Organism: Homo sapiens.
- Length: 485 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, pyloric stenosis and Esophageal atresia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | WD repeat-containing protein 13 |
|---|---|
| UniProt accession | Q9H1Z4 |
| Gene | WDR13 |
| Organism | Homo sapiens |
| Length | 485 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (60)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.27
- pyloric stenosis · score 0.11
- Esophageal atresia · score 0.11
- hyperinsulinemic hypoglycemia, familial, 2 · score 0.06
- MODY · score 0.06
- hypoinsulinemic hypoglycemia and body hemihypertrophy · score 0.06
- hyperinsulinemic hypoglycemia, familial, 1 · score 0.05
- obesity due to prohormone convertase I deficiency · score 0.05
- exercise-induced hyperinsulinism · score 0.04
- hyperinsulinism due to INSR deficiency · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H1Z4-F1 | alphafold | PREDICTED | 79.99 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H1Z4.
Amino-acid sequence (485 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WDR13?
The strongest Open Targets associations for WDR13 are neurodegenerative disease, pyloric stenosis, Esophageal atresia, hyperinsulinemic hypoglycemia, familial, 2 and MODY.
How long is the WDR13 protein?
The Homo sapiens WDR13 protein (UniProt Q9H1Z4) is 485 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H1Z4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H1Z4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.