Augurin (ECRG4)
Homo sapiens — UniProt Q9H1Z8
Data last refreshed: (UniProt release unknown)
Key facts
Augurin (ECRG4) is a protein from Homo sapiens identified by UniProt accession Q9H1Z8, 148 residues long. MolForge cross-references it against 0 known binders and 127 disease associations.
- UniProt accession: Q9H1Z8; gene symbol ECRG4.
- Organism: Homo sapiens.
- Length: 148 amino acids.
- Top disease associations (Open Targets): osteoarthritis, hip, body height and BMI-adjusted hip circumference.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Augurin |
|---|---|
| UniProt accession | Q9H1Z8 |
| Gene | ECRG4 |
| Organism | Homo sapiens |
| Length | 148 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (127)
Diseases linked to this target (Open Targets).
- osteoarthritis, hip · score 0.41
- body height · score 0.39
- BMI-adjusted hip circumference · score 0.33
- osteoarthritis · score 0.30
- total hip arthroplasty · score 0.30
- BMI-adjusted waist circumference · score 0.30
- sitting height measurement · score 0.29
- medical procedure · score 0.28
- neurofibrillary tangles measurement · score 0.25
- neuritic plaque measurement · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H1Z8-F1 | alphafold | PREDICTED | 66.07 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H1Z8.
Amino-acid sequence (148 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ECRG4?
The strongest Open Targets associations for ECRG4 are osteoarthritis, hip, body height, BMI-adjusted hip circumference, osteoarthritis and total hip arthroplasty.
How long is the ECRG4 protein?
The Homo sapiens ECRG4 protein (UniProt Q9H1Z8) is 148 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H1Z8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H1Z8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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