Melanoma-associated antigen H1 (MAGEH1)
Homo sapiens — UniProt Q9H213
Data last refreshed: (UniProt release unknown)
Key facts
Melanoma-associated antigen H1 (MAGEH1) is a protein from Homo sapiens identified by UniProt accession Q9H213, 219 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q9H213; gene symbol MAGEH1.
- Organism: Homo sapiens.
- Length: 219 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, melanoma and deafness.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Melanoma-associated antigen H1 |
|---|---|
| UniProt accession | Q9H213 |
| Gene | MAGEH1 |
| Organism | Homo sapiens |
| Length | 219 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- melanoma · score 0.07
- deafness · score 0.06
- myeloid sarcoma · score 0.06
- benign adult familial myoclonic epilepsy · score 0.04
- neoplasm · score 0.03
- hepatocellular carcinoma · score 0.03
- glioblastoma multiforme · score 0.03
- cholangiocarcinoma · score 0.02
- ulcerative colitis · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H213-F1 | alphafold | PREDICTED | 66.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H213.
Amino-acid sequence (219 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MAGEH1?
The strongest Open Targets associations for MAGEH1 are neurodegenerative disease, melanoma, deafness, myeloid sarcoma and benign adult familial myoclonic epilepsy.
How long is the MAGEH1 protein?
The Homo sapiens MAGEH1 protein (UniProt Q9H213) is 219 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H213 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H213 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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