Uncharacterized protein C1orf21 (C1orf21)
Homo sapiens — UniProt Q9H246
Data last refreshed: (UniProt release unknown)
Key facts
Uncharacterized protein C1orf21 (C1orf21) is a protein from Homo sapiens identified by UniProt accession Q9H246, 121 residues long. MolForge cross-references it against 0 known binders and 91 disease associations.
- UniProt accession: Q9H246; gene symbol C1orf21.
- Organism: Homo sapiens.
- Length: 121 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, systolic blood pressure and hypertension.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Uncharacterized protein C1orf21 |
|---|---|
| UniProt accession | Q9H246 |
| Gene | C1orf21 |
| Organism | Homo sapiens |
| Length | 121 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (91)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- systolic blood pressure · score 0.40
- hypertension · score 0.26
- diastolic blood pressure · score 0.21
- Rh deficiency syndrome · score 0.06
- chronotype measurement · score 0.06
- arterial stiffness measurement · score 0.06
- monocyte count · score 0.06
- gluthathione peroxidase deficiency · score 0.05
- dehydrated hereditary stomatocytosis · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H246-F1 | alphafold | PREDICTED | 66.26 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H246.
Amino-acid sequence (121 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C1orf21?
The strongest Open Targets associations for C1orf21 are neurodegenerative disease, systolic blood pressure, hypertension, diastolic blood pressure and Rh deficiency syndrome.
How long is the C1orf21 protein?
The Homo sapiens C1orf21 protein (UniProt Q9H246) is 121 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H246 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H246 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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