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Olfactory receptor 51E2 (OR51E2)

Homo sapiens — UniProt Q9H255

Gene: OR51E2Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Olfactory receptor 51E2 (OR51E2) is a protein from Homo sapiens identified by UniProt accession Q9H255, 320 residues long. MolForge cross-references it against 5 known binders and 35 disease associations.

  • UniProt accession: Q9H255; gene symbol OR51E2.
  • Organism: Homo sapiens.
  • Length: 320 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, medulloblastoma and ovarian cancer.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameOlfactory receptor 51E2
UniProt accessionQ9H255
GeneOR51E2
OrganismHomo sapiens
Length320 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (35)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.26
  • medulloblastoma · score 0.21
  • ovarian cancer · score 0.18
  • hepatocellular carcinoma · score 0.18
  • breast adenocarcinoma · score 0.18
  • neoplasm · score 0.04
  • breast carcinoma · score 0.04
  • prostate intraepithelial neoplasia · score 0.04
  • butyrylcholinesterase deficiency · score 0.04
  • colorectal cancer · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H255-F1alphafoldPREDICTED88.85—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H255.

Amino-acid sequence (320 residues)

MSSCNFTHAT FVLIGIPGLE KAHFWVGFPL LSMYVVAMFG NCIVVFIVRT ERSLHAPMYL FLCMLAAIDL ALSTSTMPKI LALFWFDSRE ISFEACLTQM FFIHALSAIE STILLAMAFD RYVAICHPLR HAAVLNNTVT AQIGIVAVVR GSLFFFPLPL LIKRLAFCHS NVLSHSYCVH QDVMKLAYAD TLPNVVYGLT AILLVMGVDV MFISLSYFLI IRTVLQLPSK SERAKAFGTC VSHIGVVLAF YVPLIGLSVV HRFGNSLHPI VRVVMGDIYL LLPPVINPII YGAKTKQIRT RVLAMFKISC DKDLQAVGGK

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with OR51E2?

The strongest Open Targets associations for OR51E2 are neurodegenerative disease, medulloblastoma, ovarian cancer, hepatocellular carcinoma and breast adenocarcinoma.

How long is the OR51E2 protein?

The Homo sapiens OR51E2 protein (UniProt Q9H255) is 320 amino acids long.

Browse: Targets: O · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H255
GeneOR51E2
OrganismHomo sapiens
Length320
Binders5
Diseases35
View on UniProt