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Dendritic cell-specific transmembrane protein (DCSTAMP)

Homo sapiens — UniProt Q9H295

Gene: DCSTAMPHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Dendritic cell-specific transmembrane protein (DCSTAMP) is a protein from Homo sapiens identified by UniProt accession Q9H295, 470 residues long. MolForge cross-references it against 0 known binders and 75 disease associations.

  • UniProt accession: Q9H295; gene symbol DCSTAMP.
  • Organism: Homo sapiens.
  • Length: 470 amino acids.
  • Top disease associations (Open Targets): osteitis deformans, gastric adenocarcinoma and Paralytic ileus.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameDendritic cell-specific transmembrane protein
UniProt accessionQ9H295
GeneDCSTAMP
OrganismHomo sapiens
Length470 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (75)

Diseases linked to this target (Open Targets).

  • osteitis deformans · score 0.27
  • gastric adenocarcinoma · score 0.11
  • Paralytic ileus · score 0.11
  • particulate matter air pollution measurement · score 0.11
  • self reported educational attainment · score 0.09
  • melorheostosis · score 0.05
  • dacryocystitis-osteopoikilosis syndrome · score 0.05
  • osteosclerosis-ichthyosis-premature ovarian failure syndrome · score 0.05
  • autosomal recessive osteopetrosis 6 · score 0.05
  • Intermediate osteopetrosis · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H295-F1alphafoldPREDICTED82.31—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H295.

Amino-acid sequence (470 residues)

MGIWTSGTDI FLSLWEIYVS PRSPGWMDFI QHLGVCCLVA LISVGLLSVA ACWFLPSIIA AAASWIITCV LLCCSKHARC FILLVFLSCG LREGRNALIA AGTGIVILGH VENIFHNFKG LLDGMTCNLR AKSFSIHFPL LKKYIEAIQW IYGLATPLSV FDDLVSWNQT LAVSLFSPSH VLEAQLNDSK GEVLSVLYQM ATTTEVLSSL GQKLLAFAGL SLVLLGTGLF MKRFLGPCGW KYENIYITRQ FVQFDERERH QQRPCVLPLN KEERRKYVII PTFWPTPKER KNLGLFFLPI LIHLCIWVLF AAVDYLLYRL IFSVSKQFQS LPGFEVHLKL HGEKQGTQDI IHDSSFNISV FEPNCIPKPK FLLSETWVPL SVILLILVML GLLSSILMQL KILVSASFYP SVERKRIQYL HAKLLKKRSK QPLGEVKRRL SLYLTKIHFW LPVLKMIRKK QMDMASADKS

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with DCSTAMP?

The strongest Open Targets associations for DCSTAMP are osteitis deformans, gastric adenocarcinoma, Paralytic ileus, particulate matter air pollution measurement and self reported educational attainment.

How long is the DCSTAMP protein?

The Homo sapiens DCSTAMP protein (UniProt Q9H295) is 470 amino acids long.

Browse: Targets: D · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H295
GeneDCSTAMP
OrganismHomo sapiens
Length470
Binders0
Diseases75
View on UniProt