Neurogenin-2 (NEUROG2)
Homo sapiens — UniProt Q9H2A3
Data last refreshed: (UniProt release unknown)
Key facts
Neurogenin-2 (NEUROG2) is a protein from Homo sapiens identified by UniProt accession Q9H2A3, 272 residues long. MolForge cross-references it against 0 known binders and 95 disease associations.
- UniProt accession: Q9H2A3; gene symbol NEUROG2.
- Organism: Homo sapiens.
- Length: 272 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, cortical surface area measurement and brain measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Neurogenin-2 |
|---|---|
| UniProt accession | Q9H2A3 |
| Gene | NEUROG2 |
| Organism | Homo sapiens |
| Length | 272 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (95)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.48
- cortical surface area measurement · score 0.33
- brain measurement · score 0.31
- cortical thickness · score 0.27
- diet measurement · score 0.25
- neuroimaging measurement · score 0.20
- body mass index · score 0.10
- physical activity · score 0.08
- amyotrophic lateral sclerosis · score 0.07
- glioblastoma multiforme · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2A3-F1 | alphafold | PREDICTED | 62.87 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2A3.
Amino-acid sequence (272 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NEUROG2?
The strongest Open Targets associations for NEUROG2 are neurodegenerative disease, cortical surface area measurement, brain measurement, cortical thickness and diet measurement.
How long is the NEUROG2 protein?
The Homo sapiens NEUROG2 protein (UniProt Q9H2A3) is 272 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2A3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2A3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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