C-X-C motif chemokine 16 (CXCL16)
Homo sapiens — UniProt Q9H2A7
Data last refreshed: (UniProt release unknown)
Key facts
C-X-C motif chemokine 16 (CXCL16) is a protein from Homo sapiens identified by UniProt accession Q9H2A7, 254 residues long. MolForge cross-references it against 0 known binders and 399 disease associations.
- UniProt accession: Q9H2A7; gene symbol CXCL16.
- Organism: Homo sapiens.
- Length: 254 amino acids.
- Top disease associations (Open Targets): mean platelet volume, lymphocyte count and C-X-C motif chemokine 16 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | C-X-C motif chemokine 16 |
|---|---|
| UniProt accession | Q9H2A7 |
| Gene | CXCL16 |
| Organism | Homo sapiens |
| Length | 254 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (399)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.27
- lymphocyte count · score 0.18
- C-X-C motif chemokine 16 measurement · score 0.18
- mean arterial pressure · score 0.17
- head and neck squamous cell carcinoma · score 0.16
- platelet component distribution width · score 0.14
- neoplasm · score 0.11
- cancer · score 0.10
- prostate adenocarcinoma · score 0.10
- non-small cell lung carcinoma · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2A7-F1 | alphafold | PREDICTED | 64.57 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2A7.
Amino-acid sequence (254 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CXCL16?
The strongest Open Targets associations for CXCL16 are mean platelet volume, lymphocyte count, C-X-C motif chemokine 16 measurement, mean arterial pressure and head and neck squamous cell carcinoma.
How long is the CXCL16 protein?
The Homo sapiens CXCL16 protein (UniProt Q9H2A7) is 254 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2A7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2A7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.