Carbohydrate sulfotransferase 8 (CHST8)
Homo sapiens — UniProt Q9H2A9
Data last refreshed: (UniProt release unknown)
Key facts
Carbohydrate sulfotransferase 8 (CHST8) is a protein from Homo sapiens identified by UniProt accession Q9H2A9, 424 residues long. MolForge cross-references it against 0 known binders and 151 disease associations.
- UniProt accession: Q9H2A9; gene symbol CHST8.
- Organism: Homo sapiens.
- Length: 424 amino acids.
- Top disease associations (Open Targets): peeling skin syndrome type A, protein measurement and cystatin C measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Carbohydrate sulfotransferase 8 |
|---|---|
| UniProt accession | Q9H2A9 |
| Gene | CHST8 |
| Organism | Homo sapiens |
| Length | 424 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (151)
Diseases linked to this target (Open Targets).
- peeling skin syndrome type A · score 0.40
- protein measurement · score 0.33
- cystatin C measurement · score 0.32
- gut microbiome measurement · score 0.28
- bone density · score 0.28
- peeling skin syndrome · score 0.12
- 46,XX gonadal dysgenesis · score 0.08
- primary ovarian insufficiency · score 0.07
- Testicular regression syndrome · score 0.07
- isolated congenital hypogonadotropic hypogonadism · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2A9-F1 | alphafold | PREDICTED | 79.10 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2A9.
Amino-acid sequence (424 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CHST8?
The strongest Open Targets associations for CHST8 are peeling skin syndrome type A, protein measurement, cystatin C measurement, gut microbiome measurement and bone density.
How long is the CHST8 protein?
The Homo sapiens CHST8 protein (UniProt Q9H2A9) is 424 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2A9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2A9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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