Sulfate anion transporter 1 (SLC26A1)
Homo sapiens — UniProt Q9H2B4
Data last refreshed: (UniProt release unknown)
Key facts
Sulfate anion transporter 1 (SLC26A1) is a protein from Homo sapiens identified by UniProt accession Q9H2B4, 701 residues long. MolForge cross-references it against 0 known binders and 148 disease associations.
- UniProt accession: Q9H2B4; gene symbol SLC26A1.
- Organism: Homo sapiens.
- Length: 701 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): nephrolithiasis susceptibility caused by SLC26A1, mucopolysaccharidosis type 1 and Hurler syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sulfate anion transporter 1 |
|---|---|
| UniProt accession | Q9H2B4 |
| Gene | SLC26A1 |
| Organism | Homo sapiens |
| Length | 701 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (148)
Diseases linked to this target (Open Targets).
- nephrolithiasis susceptibility caused by SLC26A1 · score 0.62
- mucopolysaccharidosis type 1 · score 0.57
- Hurler syndrome · score 0.55
- Hurler-Scheie syndrome · score 0.52
- Scheie syndrome · score 0.51
- nephrolithiasis · score 0.51
- calcium oxalate urolithiasis · score 0.46
- hypersulfaturia · score 0.45
- Interstitial pneumonitis · score 0.34
- mucopolysaccharidosis · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2B4-F1 | alphafold | PREDICTED | 82.65 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2B4.
Amino-acid sequence (701 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC26A1?
The strongest Open Targets associations for SLC26A1 are nephrolithiasis susceptibility caused by SLC26A1, mucopolysaccharidosis type 1, Hurler syndrome, Hurler-Scheie syndrome and Scheie syndrome.
How long is the SLC26A1 protein?
The Homo sapiens SLC26A1 protein (UniProt Q9H2B4) is 701 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2B4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2B4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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