LIM/homeobox protein Lhx5 (LHX5)
Homo sapiens — UniProt Q9H2C1
Data last refreshed: (UniProt release unknown)
Key facts
LIM/homeobox protein Lhx5 (LHX5) is a protein from Homo sapiens identified by UniProt accession Q9H2C1, 402 residues long. MolForge cross-references it against 0 known binders and 50 disease associations.
- UniProt accession: Q9H2C1; gene symbol LHX5.
- Organism: Homo sapiens.
- Length: 402 amino acids.
- Top disease associations (Open Targets): mathematical ability, self reported educational attainment and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | LIM/homeobox protein Lhx5 |
|---|---|
| UniProt accession | Q9H2C1 |
| Gene | LHX5 |
| Organism | Homo sapiens |
| Length | 402 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (50)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.35
- self reported educational attainment · score 0.34
- body mass index · score 0.30
- cognitive function measurement · score 0.28
- cerebrospinal fluid biomarker measurement · score 0.23
- diabetic ketoacidosis · score 0.21
- testosterone measurement · score 0.17
- smoking behavior · score 0.16
- type 2 diabetes mellitus · score 0.11
- glioblastoma multiforme · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2C1-F1 | alphafold | PREDICTED | 67.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2C1.
Amino-acid sequence (402 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LHX5?
The strongest Open Targets associations for LHX5 are mathematical ability, self reported educational attainment, body mass index, cognitive function measurement and cerebrospinal fluid biomarker measurement.
How long is the LHX5 protein?
The Homo sapiens LHX5 protein (UniProt Q9H2C1) is 402 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2C1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2C1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.