Protein ARV1 (ARV1)
Homo sapiens — UniProt Q9H2C2
Data last refreshed: (UniProt release unknown)
Key facts
Protein ARV1 (ARV1) is a protein from Homo sapiens identified by UniProt accession Q9H2C2, 271 residues long. MolForge cross-references it against 0 known binders and 92 disease associations.
- UniProt accession: Q9H2C2; gene symbol ARV1.
- Organism: Homo sapiens.
- Length: 271 amino acids.
- Top disease associations (Open Targets): developmental and epileptic encephalopathy, genetic disorder and Abnormality of the nervous system.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein ARV1 |
|---|---|
| UniProt accession | Q9H2C2 |
| Gene | ARV1 |
| Organism | Homo sapiens |
| Length | 271 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (92)
Diseases linked to this target (Open Targets).
- developmental and epileptic encephalopathy · score 0.53
- genetic disorder · score 0.46
- Abnormality of the nervous system · score 0.27
- Blindness · score 0.26
- Neurodegeneration · score 0.26
- hemoglobin measurement · score 0.18
- hematocrit · score 0.17
- red blood cell density measurement · score 0.14
- erythrocyte count · score 0.14
- hypertriglyceridemia 2 · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2C2-F1 | alphafold | PREDICTED | 81.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2C2.
Amino-acid sequence (271 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ARV1?
The strongest Open Targets associations for ARV1 are developmental and epileptic encephalopathy, genetic disorder, Abnormality of the nervous system, Blindness and Neurodegeneration.
How long is the ARV1 protein?
The Homo sapiens ARV1 protein (UniProt Q9H2C2) is 271 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2C2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2C2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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