Enhancer of polycomb homolog 1 (EPC1)
Homo sapiens — UniProt Q9H2F5
Data last refreshed: (UniProt release unknown)
Key facts
Enhancer of polycomb homolog 1 (EPC1) is a protein from Homo sapiens identified by UniProt accession Q9H2F5, 836 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q9H2F5; gene symbol EPC1.
- Organism: Homo sapiens.
- Length: 836 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, BMI-adjusted waist-hip ratio and hair shape measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Enhancer of polycomb homolog 1 |
|---|---|
| UniProt accession | Q9H2F5 |
| Gene | EPC1 |
| Organism | Homo sapiens |
| Length | 836 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- BMI-adjusted waist-hip ratio · score 0.40
- hair shape measurement · score 0.36
- waist-hip ratio · score 0.32
- balding measurement · score 0.32
- platelet component distribution width · score 0.31
- peak expiratory flow · score 0.26
- FEV/FVC ratio · score 0.25
- diastolic blood pressure · score 0.25
- BMI-adjusted waist circumference · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2F5-F1 | alphafold | PREDICTED | 56.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2F5.
Amino-acid sequence (836 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EPC1?
The strongest Open Targets associations for EPC1 are neurodegenerative disease, BMI-adjusted waist-hip ratio, hair shape measurement, waist-hip ratio and balding measurement.
How long is the EPC1 protein?
The Homo sapiens EPC1 protein (UniProt Q9H2F5) is 836 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2F5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2F5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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