Coiled-coil domain-containing protein 68 (CCDC68)
Homo sapiens — UniProt Q9H2F9
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil domain-containing protein 68 (CCDC68) is a protein from Homo sapiens identified by UniProt accession Q9H2F9, 335 residues long. MolForge cross-references it against 0 known binders and 88 disease associations.
- UniProt accession: Q9H2F9; gene symbol CCDC68.
- Organism: Homo sapiens.
- Length: 335 amino acids.
- Top disease associations (Open Targets): mean platelet volume, platelet count and age-related hearing impairment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil domain-containing protein 68 |
|---|---|
| UniProt accession | Q9H2F9 |
| Gene | CCDC68 |
| Organism | Homo sapiens |
| Length | 335 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (88)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.46
- platelet count · score 0.46
- age-related hearing impairment · score 0.39
- schizophrenia · score 0.37
- unipolar depression · score 0.35
- adolescent idiopathic scoliosis · score 0.34
- pancreatic carcinoma · score 0.34
- wellbeing measurement · score 0.33
- mathematical ability · score 0.33
- diastolic blood pressure · score 0.33
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2F9-F1 | alphafold | PREDICTED | 80.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2F9.
Amino-acid sequence (335 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCDC68?
The strongest Open Targets associations for CCDC68 are mean platelet volume, platelet count, age-related hearing impairment, schizophrenia and unipolar depression.
How long is the CCDC68 protein?
The Homo sapiens CCDC68 protein (UniProt Q9H2F9) is 335 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2F9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2F9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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