Golgin-45 (BLZF1)
Homo sapiens — UniProt Q9H2G9
Data last refreshed: (UniProt release unknown)
Key facts
Golgin-45 (BLZF1) is a protein from Homo sapiens identified by UniProt accession Q9H2G9, 400 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q9H2G9; gene symbol BLZF1.
- Organism: Homo sapiens.
- Length: 400 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, electrocardiography and QT interval.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Golgin-45 |
|---|---|
| UniProt accession | Q9H2G9 |
| Gene | BLZF1 |
| Organism | Homo sapiens |
| Length | 400 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.31
- electrocardiography · score 0.19
- QT interval · score 0.16
- venous thromboembolism · score 0.16
- acute myeloid leukemia · score 0.15
- pulse pressure measurement · score 0.08
- blood coagulation disease · score 0.07
- gastrointestinal stromal tumor · score 0.03
- Ovarian Endometriosis · score 0.03
- handedness · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2G9-F1 | alphafold | PREDICTED | 71.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2G9.
Amino-acid sequence (400 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BLZF1?
The strongest Open Targets associations for BLZF1 are neurodegenerative disease, electrocardiography, QT interval, venous thromboembolism and acute myeloid leukemia.
How long is the BLZF1 protein?
The Homo sapiens BLZF1 protein (UniProt Q9H2G9) is 400 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2G9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2G9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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