Peptidyl-prolyl cis-trans isomerase-like 3 (PPIL3)
Homo sapiens — UniProt Q9H2H8
Data last refreshed: (UniProt release unknown)
Key facts
Peptidyl-prolyl cis-trans isomerase-like 3 (PPIL3) is a protein from Homo sapiens identified by UniProt accession Q9H2H8, 161 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.
- UniProt accession: Q9H2H8; gene symbol PPIL3.
- Organism: Homo sapiens.
- Length: 161 amino acids.
- Top disease associations (Open Targets): hepatocellular carcinoma, Red cell distribution width and total blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Peptidyl-prolyl cis-trans isomerase-like 3 |
|---|---|
| UniProt accession | Q9H2H8 |
| Gene | PPIL3 |
| Organism | Homo sapiens |
| Length | 161 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- hepatocellular carcinoma · score 0.09
- Red cell distribution width · score 0.09
- total blood protein measurement · score 0.06
- cholesterol-ester transfer protein deficiency · score 0.05
- hypertriglyceridemia 2 · score 0.05
- mean platelet volume · score 0.05
- Combined hyperlipidemia · score 0.04
- body height · score 0.04
- neoplasm · score 0.04
- thyroid hormone metabolism, abnormal, 2 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2H8-F1 | alphafold | PREDICTED | 96.36 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2H8.
Amino-acid sequence (161 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PPIL3?
The strongest Open Targets associations for PPIL3 are hepatocellular carcinoma, Red cell distribution width, total blood protein measurement, cholesterol-ester transfer protein deficiency and hypertriglyceridemia 2.
How long is the PPIL3 protein?
The Homo sapiens PPIL3 protein (UniProt Q9H2H8) is 161 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2H8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2H8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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