Sodium-coupled neutral amino acid symporter 1 (SLC38A1)
Homo sapiens — UniProt Q9H2H9
Data last refreshed: (UniProt release unknown)
Key facts
Sodium-coupled neutral amino acid symporter 1 (SLC38A1) is a protein from Homo sapiens identified by UniProt accession Q9H2H9, 487 residues long. MolForge cross-references it against 0 known binders and 148 disease associations.
- UniProt accession: Q9H2H9; gene symbol SLC38A1.
- Organism: Homo sapiens.
- Length: 487 amino acids.
- Top disease associations (Open Targets): eosinophil count, neurodegenerative disease and body weight.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sodium-coupled neutral amino acid symporter 1 |
|---|---|
| UniProt accession | Q9H2H9 |
| Gene | SLC38A1 |
| Organism | Homo sapiens |
| Length | 487 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (148)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.40
- neurodegenerative disease · score 0.38
- body weight · score 0.36
- body height · score 0.33
- posterior uveitis · score 0.31
- birth weight · score 0.31
- lean body mass · score 0.27
- protein measurement · score 0.25
- PHF-tau measurement · score 0.25
- type 1 diabetes mellitus · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2H9-F1 | alphafold | PREDICTED | 79.89 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2H9.
Amino-acid sequence (487 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC38A1?
The strongest Open Targets associations for SLC38A1 are eosinophil count, neurodegenerative disease, body weight, body height and posterior uveitis.
How long is the SLC38A1 protein?
The Homo sapiens SLC38A1 protein (UniProt Q9H2H9) is 487 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2H9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2H9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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