Phosducin-like protein 3 (PDCL3)
Homo sapiens — UniProt Q9H2J4
Data last refreshed: (UniProt release unknown)
Key facts
Phosducin-like protein 3 (PDCL3) is a protein from Homo sapiens identified by UniProt accession Q9H2J4, 239 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.
- UniProt accession: Q9H2J4; gene symbol PDCL3.
- Organism: Homo sapiens.
- Length: 239 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, mathematical ability and Alzheimer disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Phosducin-like protein 3 |
|---|---|
| UniProt accession | Q9H2J4 |
| Gene | PDCL3 |
| Organism | Homo sapiens |
| Length | 239 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.27
- mathematical ability · score 0.21
- Alzheimer disease · score 0.18
- age at onset · score 0.18
- intelligence · score 0.13
- cancer · score 0.07
- neoplasm · score 0.03
- cognitive function measurement · score 0.03
- hepatocellular carcinoma · score 0.02
- malignant glioma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2J4-F1 | alphafold | PREDICTED | 79.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2J4.
Amino-acid sequence (239 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PDCL3?
The strongest Open Targets associations for PDCL3 are self reported educational attainment, mathematical ability, Alzheimer disease, age at onset and intelligence.
How long is the PDCL3 protein?
The Homo sapiens PDCL3 protein (UniProt Q9H2J4) is 239 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2J4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2J4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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