Sodium-dependent neutral amino acid transporter B(0)AT2 (SLC6A15)
Homo sapiens — UniProt Q9H2J7
Data last refreshed: (UniProt release unknown)
Key facts
Sodium-dependent neutral amino acid transporter B(0)AT2 (SLC6A15) is a protein from Homo sapiens identified by UniProt accession Q9H2J7, 730 residues long. MolForge cross-references it against 1 known binders and 60 disease associations.
- UniProt accession: Q9H2J7; gene symbol SLC6A15.
- Organism: Homo sapiens.
- Length: 730 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): hair colour measurement, neurodegenerative disease and cutaneous melanoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sodium-dependent neutral amino acid transporter B(0)AT2 |
|---|---|
| UniProt accession | Q9H2J7 |
| Gene | SLC6A15 |
| Organism | Homo sapiens |
| Length | 730 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (60)
Diseases linked to this target (Open Targets).
- hair colour measurement · score 0.30
- neurodegenerative disease · score 0.22
- cutaneous melanoma · score 0.18
- body height · score 0.17
- PR interval · score 0.17
- tendinitis · score 0.17
- unipolar depression · score 0.14
- isolated asymptomatic elevation of creatine phosphokinase · score 0.07
- smoking behaviour measurement · score 0.06
- depressive symptom measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2J7-F1 | alphafold | PREDICTED | 79.71 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2J7.
Amino-acid sequence (730 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC6A15?
The strongest Open Targets associations for SLC6A15 are hair colour measurement, neurodegenerative disease, cutaneous melanoma, body height and PR interval.
How long is the SLC6A15 protein?
The Homo sapiens SLC6A15 protein (UniProt Q9H2J7) is 730 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2J7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2J7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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