Translation initiation factor IF-3, mitochondrial (MTIF3)
Homo sapiens — UniProt Q9H2K0
Data last refreshed: (UniProt release unknown)
Key facts
Translation initiation factor IF-3, mitochondrial (MTIF3) is a protein from Homo sapiens identified by UniProt accession Q9H2K0, 278 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.
- UniProt accession: Q9H2K0; gene symbol MTIF3.
- Organism: Homo sapiens.
- Length: 278 amino acids.
- Top disease associations (Open Targets): body mass index, Red cell distribution width and body weight.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Translation initiation factor IF-3, mitochondrial |
|---|---|
| UniProt accession | Q9H2K0 |
| Gene | MTIF3 |
| Organism | Homo sapiens |
| Length | 278 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (49)
Diseases linked to this target (Open Targets).
- body mass index · score 0.35
- Red cell distribution width · score 0.26
- body weight · score 0.25
- lean body mass · score 0.21
- body fat percentage · score 0.16
- fat body mass · score 0.16
- base metabolic rate measurement · score 0.15
- whole body water mass · score 0.12
- hip circumference · score 0.10
- waist circumference · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2K0-F1 | alphafold | PREDICTED | 78.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2K0.
Amino-acid sequence (278 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MTIF3?
The strongest Open Targets associations for MTIF3 are body mass index, Red cell distribution width, body weight, lean body mass and body fat percentage.
How long is the MTIF3 protein?
The Homo sapiens MTIF3 protein (UniProt Q9H2K0) is 278 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2K0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2K0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.