Serine/threonine-protein kinase TAO3 (TAOK3)
Homo sapiens — UniProt Q9H2K8
Data last refreshed: (UniProt release unknown)
Key facts
Serine/threonine-protein kinase TAO3 (TAOK3) is a protein from Homo sapiens identified by UniProt accession Q9H2K8, 898 residues long. MolForge cross-references it against 18 known binders and 87 disease associations.
- UniProt accession: Q9H2K8; gene symbol TAOK3.
- Organism: Homo sapiens.
- Length: 898 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, neuroticism measurement and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine/threonine-protein kinase TAO3 |
|---|---|
| UniProt accession | Q9H2K8 |
| Gene | TAOK3 |
| Organism | Homo sapiens |
| Length | 898 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (87)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- neuroticism measurement · score 0.46
- Red cell distribution width · score 0.45
- depressive symptom measurement · score 0.29
- wellbeing measurement · score 0.28
- hemoglobin A1 measurement · score 0.27
- blood protein measurement · score 0.25
- loneliness measurement · score 0.21
- type 1 diabetes mellitus · score 0.17
- diabetes mellitus · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H2K8-F1 | alphafold | PREDICTED | 80.65 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H2K8.
Amino-acid sequence (898 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TAOK3?
The strongest Open Targets associations for TAOK3 are neurodegenerative disease, neuroticism measurement, Red cell distribution width, depressive symptom measurement and wellbeing measurement.
How long is the TAOK3 protein?
The Homo sapiens TAOK3 protein (UniProt Q9H2K8) is 898 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H2K8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H2K8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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